Sermorelin Therapy
Support Your Body's Own Growth Hormone Release
Growth hormone helps regulate sleep, body composition, energy and recovery, and the amount your body releases naturally drops as you age. Sermorelin is a peptide that encourages your pituitary gland to release more of your own growth hormone, rather than replacing it from the outside.
Elevera Health offers sermorelin as an injection or a dissolving tablet (troche), prescribed after a telehealth visit and monitored with lab work.
- Injection or dissolving tablet (troche)
- Guided by your symptoms and IGF-1 lab results
- Follow-ups with the same provider
- Telehealth visits for patients in VA, MD, DC and WV
What Is Sermorelin?
Sermorelin is a lab-made version of the first 29 amino acids of growth hormone-releasing hormone (GHRH), the natural signal your brain uses to tell the pituitary gland to release growth hormone.
Because it works through your body’s own system, growth hormone is still released in natural pulses, and your body’s normal feedback controls stay in place. That’s different from taking growth hormone (HGH) directly.
A brand-name version of sermorelin was FDA-approved in the past and later discontinued by its maker. The sermorelin we prescribe today is compounded by a licensed pharmacy and is not FDA-approved.
What the Research Says
Studies in adults, most of them small, have looked at how sermorelin affects growth hormone and the body. Results vary from person to person, and changes are gradual.
Growth Hormone and IGF-1
Sermorelin raises growth hormone release and IGF-1, a marker your provider can track with a simple blood test to see how you’re responding.
Sleep
Most growth hormone is released during deep sleep, and GHRH plays a role in deep sleep. Some patients notice changes in sleep quality.
Body Composition
Small studies in older adults have looked at changes in lean body mass and body fat. Results depend on your starting point, along with nutrition, strength training and sleep.
Energy and Recovery
Some patients report better energy and recovery from exercise. These effects are less well studied, and they take time, often a few months.
Injection or Troche: How Sermorelin Is Taken
- Injection: a small injection just under the skin, usually in the evening at bedtime, when your body naturally releases the most growth hormone
- Troche: a tablet that dissolves between your cheek and gum, for people who prefer not to use needles. Less is known about how well it's absorbed than the injection.
- Your provider recommends the form, dose and schedule based on your goals, labs and preferences
- Labs, including IGF-1, are checked before you start and during treatment to guide your dose
- Best paired with good sleep, strength training and enough protein
How to Get Started
Sermorelin is a prescription medication, so every plan starts with a visit.
1. Book a Visit
Schedule a telehealth appointment at a time that works for you, including evenings.
2. Labs and Review
Talk through your goals, sleep, energy and health history. Your provider orders baseline labs, such as IGF-1, when needed.
3. Your Plan
If sermorelin is a good fit, your provider recommends the injection or troche, and the pharmacy ships it to your door.
4. Follow Up
Check in with the same provider, repeat labs and adjust your dose over time.
Safety: What to Know
- Compounded sermorelin is not FDA-approved and hasn't been reviewed by the FDA for safety or effectiveness.
- Common side effects are mild: redness, swelling or soreness where the injection is given, flushing, headache or dizziness.
- Sermorelin isn't recommended during pregnancy or breastfeeding, or for people with active cancer or a history of cancer.
- An underactive thyroid can affect how well sermorelin works, so your provider may check your thyroid first.
- Competitive athletes: sermorelin and other growth hormone-releasing peptides are on the World Anti-Doping Agency (WADA) prohibited list.
Related Services & Resources
Frequently Asked Questions
Sermorelin signals your pituitary gland to release more of your own growth hormone, which raises IGF-1. Patients and studies have looked at changes in sleep, body composition, energy and recovery, but results vary and take time.
No. HGH replaces growth hormone directly. Sermorelin prompts your body to make and release its own, so your natural pulses and feedback controls stay in place.
The injection is the most studied form. The troche dissolves in your mouth, which some people prefer, but less is known about how well it’s absorbed. Your provider will help you choose.
Some people notice sleep changes within a few weeks. Changes in energy and body composition, when they happen, usually take a few months. Your provider tracks your progress with follow-ups and labs.
Usually, yes. An IGF-1 level before you start and during treatment helps your provider see how you’re responding and adjust your dose. Your provider may also check thyroid function.
A brand-name version was FDA-approved in the past and later discontinued by its maker. The compounded sermorelin available today is not FDA-approved.
Current sermorelin prices are on our price sheet. Compounded peptides generally aren’t covered by insurance.
Find Out If Sermorelin Is Right for You
Book a telehealth visit to talk through your sleep, energy and goals with a provider who'll stay with you the whole way.
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